Location
22nd Street and Fairmount Avenue, just five blocks from the Philadelphia Museum of Art.

Parking:
There is ample on-street parking and a parking lot right next door.

From the North or West:
- Take Interstate 76 (the Schuylkill Expressway) to Exit 344 (Old Exit 38), which is Interstate 676, also know as the Vine Street Expressway.
- On I-676 take the first exit, "Benjamin Franklin Parkway/ 23 Street."
- Take the first left onto 22nd Street.
- Pass the Philadelphia Museum of Art (on your left) and continue five blocks north, to Fairmount Avenue.

From the South or East:
- Take I-95 to Exit 22 (Old Exit 17) and follow Interstate 676 West.
- Follow Interstate 676 West.
- Get off at Art Museum/ Benjamin Franklin Parkway" Exit.
- At the top of the ramp, turn right onto 22nd street.
- Pass the Philadelphia Museum of Art (on your left) and continue five blocks north, to Fairmount Avenue.

Bus and Trolley Service: Eastern State Penitentiary is convenient to SEPTA bus routes: 76, 48, 43, 33, 32, 7 the Phlash Tourist Bus Line, and the Philadelphia Trolley Works route.